2026 Super Bowl Odds: 49ers Claim Top Spot After 6-0 Start

Ever since Myles Garrett was traded to the Rams in early June, L.A. had been favored to win the Super Bowl. That reign is now over. In Week 6, the Rams fell to 2-4 after a stunning loss to the Cardinals, who won outright as 12.5-point underdogs — the largest upset by point spread this season. L.A. is just the fifth outright preseason Super Bowl favorite in the past 50 seasons to have a losing record through six games. None of the previous four reached a conference championship game. Instead, it's their division rival who has taken over as the new favorite. Let’s take a look at the latest Super Bowl odds at DraftKings Sportsbook as of Oct. 19. This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports. 49ers: +540Bills: +750Chiefs: +750Ravens: +1000Rams: +1200Seahawks: +1200Jaguars: +1300Bears: +1500Patriots: +1800Vikings: +1800Bengals: +1900Broncos: +2000Lions: +2600Packers: +3000Cowboys: +3500Texans: +3500Panthers: +5500Falcons: +7000Raiders: +9000Steelers: +12000Colts: +12000Buccaneers: +12500Giants: +12500Commanders: +12500Saints: +15000Eagles: +20000Browns: +20000Cardinals: +40000Jets: +50000Chargers: +50000Titans: +100000Dolphins: +100000 Here's what to know about the Super Bowl LXI oddsboard: New Favorite: The 49ers have passed the Rams as the outright Super Bowl favorites at +540 after their 23-17 win over the Commanders on Monday night. The 49ers are 6-0 for the first time since 2019, when they reached the Super Bowl. It’s their second time starting 6-0 under Kyle Shanahan. Brock Purdy is playing at an MVP level and has now reached the 1,500 career pass attempts needed to qualify for the NFL’s all-time passer rating leaderboard. His 105.6 career passer rating is the highest in NFL history. Meanwhile, the Rams have dropped to fourth on the oddsboard at +1200 after their shocking loss to the Cardinals. At 2-4, L.A. has an early hole to dig itself out of. Buffalo Rises: The Bills followed their thrilling 37-34 overtime win over the Rams with a victory over the Raiders in Las Vegas, improving to 5-1. Buffalo now sits second on the Super Bowl oddsboard at +750, up from +800 last week. After opening 3-0 and stumbling against the Patriots, the Bills have won two straight as they chase their first Super Bowl title. Packers and Patriots: Green Bay has looked like a different team over the past two weeks, following its blowout of Chicago with a dominant win over Dallas. The Packers have shut down two explosive offenses in consecutive weeks, shortening their Super Bowl odds from +6500 to +3000. New England also handled business, moving from +2000 to +1800 as Drake Maye continued his in-season turnaround. Maye is the first Patriots quarterback with at least three touchdown passes in three straight games since Tom Brady in 2017. After throwing one touchdown and six interceptions in his first three games, Maye has 10 touchdowns and just one interception in Weeks 4-6. Biggest Fallers: The Chargers’ nightmare start continued as they fell to 0-6 for the first time since 2000, when they opened 0-11. Their current head coach, Jim Harbaugh, started at quarterback in Weeks 5-10 that season. L.A.’s Super Bowl odds have tumbled to +50000, a massive drop from +1600 before the season. Philadelphia is also heading in the wrong direction. For the first time in franchise history, the Eagles have followed a 2-0 start with four straight losses. Now, with Jalen Hurts ruled out for the rest of the season, their Super Bowl odds have fallen to +20000, the longest they've been all year.